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White Blood Cell Count

The total number of infection-fighting white blood cells.

Typical reference range3.8–10.8 x10E3/uL
Commonly cited optimal range4–7 x10E3/uL

Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.

What it measures

White blood cells are immune cells made in the bone marrow. The five main types are neutrophils, lymphocytes, monocytes, eosinophils and basophils, each reported in the differential.

Why it matters

WBC count screens for infection, inflammation, immune suppression and blood disorders. Within the normal range, persistently higher counts are associated with chronic low-grade inflammation and cardiovascular risk.

What a high result can mean

High counts commonly result from bacterial infection, inflammation, physical or emotional stress, smoking, corticosteroids, obesity and recent intense exercise. Very high or persistently unexplained counts can indicate leukemia or other marrow disorders.

What a low result can mean

Low counts can occur with viral infections, autoimmune disease, certain medications (chemotherapy, some antibiotics, antithyroid drugs), B12/folate deficiency and bone marrow problems. Mildly low counts are common and benign in some people, particularly those of African or Middle Eastern ancestry (benign ethnic neutropenia).

What affects the result

Counts vary through the day and rise with stress, exercise and smoking. Steroids raise neutrophils and lower lymphocytes and eosinophils. Always interpret the differential, especially absolute counts.

Units and conversion

Usually reported in x10E3/uL.

More about lab units

Also called on lab reports

WBC, White Blood Cells, WBC Count, Leukocytes, White Cell Count, Leukocyte Count, Total WBC

Related tests: White Blood Cells & Differential

This page is educational and does not replace advice from a healthcare professional.