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RDW

A measure of how much red blood cells vary in size.

Typical reference range11–15 %
Commonly cited optimal rangebelow 13.5 %

Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.

What it measures

Red cell distribution width expresses the variation in red cell volume. A high RDW means a mix of small and large cells (anisocytosis).

Why it matters

RDW often rises early in iron, B12 or folate deficiency, before MCV changes. Elevated RDW is also independently associated with cardiovascular disease, inflammation and mortality.

What a high result can mean

High RDW occurs with iron, B12 or folate deficiency, mixed deficiencies, recent blood loss or transfusion, hemolysis, recovery from anemia, liver disease and chronic inflammation.

What a low result can mean

Low RDW is not clinically significant.

What affects the result

Some labs report RDW-SD in fL instead of RDW-CV in %; these are not interchangeable. Interpret with MCV and iron, B12 and folate status.

Unit

Usually reported in %.

Also called on lab reports

RDW-CV, Red Cell Distribution Width, Red Blood Cell Distribution Width, RDW CV

Related tests: Red Blood Cells

This page is educational and does not replace advice from a healthcare professional.