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MCV

The average size of your red blood cells.

Typical reference range80–100 fL

Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.

What it measures

Mean corpuscular volume measures the average volume of a red blood cell, in femtoliters. It is used to classify anemia as microcytic (small cells), normocytic or macrocytic (large cells).

Why it matters

MCV points toward the cause of anemia and can reveal nutrient deficiencies or alcohol effects before anemia develops.

What a high result can mean

Large cells (macrocytosis) occur with B12 or folate deficiency, alcohol use, liver disease, hypothyroidism, certain medications (methotrexate, hydroxyurea, some HIV drugs), high reticulocyte counts and myelodysplasia.

What a low result can mean

Small cells (microcytosis) occur with iron deficiency, thalassemia trait, anemia of chronic disease and, rarely, lead poisoning or sideroblastic anemia.

What affects the result

Combined iron and B12 deficiency can produce a normal MCV with a high RDW. Interpret with RDW, MCH, ferritin and B12.

Units and conversion

Usually reported in fL.

More about lab units

Also called on lab reports

Mean Corpuscular Volume, Mean Cell Volume

Related tests: Red Blood Cells

This page is educational and does not replace advice from a healthcare professional.