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Urine Albumin/Creatinine Ratio

The amount of albumin leaking into urine, an early sign of kidney or blood vessel damage.

Typical reference rangebelow 29 mg/g
Commonly cited optimal rangebelow 10 mg/g

Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.

What it measures

Healthy kidneys keep albumin in the blood. UACR measures albumin in a spot urine sample, divided by urine creatinine to correct for how concentrated the urine is.

Why it matters

Elevated UACR is often the earliest sign of kidney damage from diabetes or high blood pressure, appearing before eGFR falls. It also independently predicts cardiovascular disease.

What a high result can mean

Values of 30-300 mg/g indicate moderately increased albuminuria and above 300 severely increased. Causes include diabetes, hypertension, kidney disease and metabolic syndrome; vigorous exercise, fever, urinary infection, menstrual contamination and very high protein intake can temporarily raise it.

What a low result can mean

Low values are normal and desirable.

What affects the result

A first-morning sample is preferred. Because of day-to-day variability, two of three samples over 3-6 months should be elevated to confirm. Blood pressure control, glucose control and medications like ACE inhibitors, ARBs and SGLT2 inhibitors reduce albuminuria.

Units and conversion

Usually reported in mg/g.

More about lab units

Also called on lab reports

Albumin/Creatinine Ratio, Microalbumin/Creatinine Ratio, UACR, Albumin/Creatinine Ratio, Random Urine, Microalb/Creat Ratio, Alb/Creat Ratio, Alb/Creat Ratio, Random, Microalbumin/Creatinine Ratio, Random Urine, ACR

Related tests: Kidney Function

This page is educational and does not replace advice from a healthcare professional.