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Total Testosterone

The total amount of the main androgen in the blood, both bound and free.

Typical reference range (male)264–916 ng/dL
Typical reference range (female)8–48 ng/dL

Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.

What it measures

Testosterone is produced mainly by the testes in men and by the ovaries and adrenal glands in women, under the control of LH from the pituitary. Most circulating testosterone is bound to SHBG or albumin; only 1-3% is free.

Why it matters

In men, testosterone supports libido, erectile function, muscle and bone mass, red cell production and mood; low levels define hypogonadism when accompanied by symptoms. In women, elevated testosterone is a key feature of PCOS.

What a high result can mean

In men, high values usually reflect testosterone or anabolic steroid use, or high SHBG. In women, elevated testosterone suggests PCOS, congenital adrenal hyperplasia or, rarely, androgen-secreting tumors.

What a low result can mean

Low testosterone in men can result from obesity, insulin resistance, sleep apnea, poor sleep, opioid or glucocorticoid use, chronic illness, heavy alcohol use, prior anabolic steroid use, pituitary disorders, testicular failure and aging. Low SHBG can make total testosterone appear low while free testosterone is normal.

What affects the result

Testosterone peaks in the early morning and is about 20-30% lower in the afternoon; test between roughly 7 and 10 am, ideally fasting, since glucose lowers it. Diagnosis of deficiency requires two low morning values. LC/MS/MS is more accurate than immunoassay, especially at low (female) levels. Interpret with SHBG, free testosterone, LH, FSH and estradiol.

Units and conversion

Usually reported in ng/dL.

More about lab units

Also called on lab reports

Testosterone, Testosterone, Total, TESTOSTERONE, TOTAL, MS, Testosterone, Total, LC/MS, Testosterone, Serum, Testosterone Total, Testosterone, Total, LC/MS/MS, Testosterone, Total, Immunoassay

Related tests: Sex Hormones

This page is educational and does not replace advice from a healthcare professional.