Total Protein
The total amount of albumin and globulins in the blood.
| Typical reference range | 6.1–8.1 g/dL |
Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.
What it measures
Total protein measures all proteins in serum, mainly albumin (made by the liver) and globulins (including antibodies, transport proteins and clotting-related proteins).
Why it matters
It provides a broad view of nutritional status, liver function, kidney protein loss and immune activity. Abnormal values prompt a look at the albumin/globulin split.
What a high result can mean
High values can reflect dehydration, chronic inflammation or infection (raising globulins), or increased antibody production, including multiple myeloma and other plasma cell disorders.
What a low result can mean
Low values may reflect malnutrition, malabsorption, liver disease, kidney protein loss (nephrotic syndrome), overhydration or severe burns.
What affects the result
Dehydration and prolonged tourniquet time raise it; lying down before the draw slightly lowers it. Interpret with albumin, globulin and A/G ratio; serum protein electrophoresis can follow up abnormal globulins.
Units and conversion
Usually reported in g/dL.
- From g/L: multiply by 0.1 to get g/dL
Also called on lab reports
Protein, Total, Protein, Protein, Total, Serum, Total Protein, Serum
Related tests: Blood Proteins
This page is educational and does not replace advice from a healthcare professional.