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Amylase

A starch-digesting enzyme produced by the pancreas and salivary glands.

Typical reference range21–101 U/L

Ranges vary by laboratory, method, age and sex: always use the range printed on your own report. Why labs differ.

What it measures

Amylase breaks down starches into sugars. About 40% of blood amylase comes from the pancreas and the rest mainly from the salivary glands.

Why it matters

Amylase rises in acute pancreatitis, though lipase is more specific and stays elevated longer. It also helps evaluate salivary gland disorders.

What a high result can mean

High levels occur with acute pancreatitis, gallstones blocking the pancreatic duct, salivary gland inflammation (mumps, stones), bowel obstruction or perforation, kidney disease and macroamylasemia (a benign condition where amylase binds antibodies).

What a low result can mean

Low levels can occur with chronic pancreatitis, cystic fibrosis, and are associated with obesity, metabolic syndrome and fatty liver.

What affects the result

Not very specific; interpret with lipase and symptoms. Kidney impairment reduces clearance and raises levels.

Units and conversion

Usually reported in U/L.

More about lab units

Also called on lab reports

Amylase, Serum, Amylase, Total

Related tests: Pancreas

This page is educational and does not replace advice from a healthcare professional.